Anthrax laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Laboratory Findings

The following tests are used in the diagnosis and monitoring of systemic anthrax:

Laboratory findings

Test	Initial Findings	Serial Monitoring
CBC	Hemoconcentration Possible Thrombocytopenia Leukocyte count commonly normal	Anemia Thrombocytopenia Leukocytosis (late in disease)
Electrolyte, Renal Panel, Lactate Level	Decreased Na+ level Increased BUN
Liver Enzymes, Serum Albumin	Elevated transaminase levels hypoalbuminemia
PT, PTT, D-dimer, Fibrinogen	Normal PT/PTT does not exclude DIC or coagulopathy	Low threshold for hypercoagulability workup: Haptoglobin LDH Fibrin split products ADAMTS 13 if hemolytic anemia
C-Reactive Protein	Characterization of Inflammatory Response Typically low CRP in injection anthrax
Gram Stain, Cultures, Toxic Assays	Blood Serum CSF Pleural fluid Ascites Wound exudate Bronchial exudate	[[]]