Group B streptococcal infection future or investigational therapies
Group B Streptococcal Infection Microchapters |
Differentiating Group B Streptococcal Infection from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
There is no Group B streptococcus (GBS) vaccine currently available to help mothers protect their newborns from GBS disease. Researchers are working on developing a vaccine, which may become available one day in the future. Phase I and II clinical trials among healthy, nonpregnant adults of monovalent polysaccharide-protein conjugate vaccines of GBS disease-associated types have shown these vaccines to be well tolerated and immunogenic. A recent, double-blind randomized trial of a conjugate vaccine against GBS serotype III among nonpregnant women of reproductive age found a significant delay in acquisition of colonization with the vaccine-serotype among vaccine recipients.[1]