Minimal change disease historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, Serge Korjian
Overview
Minimal change disease was first described by F. Munk in 1913, when he coined the term “lipoid nephrosis” following the observation of lipid-laden macrophages in the proximal tubular epithelial cells and oval fat bodies in urine.[1] In 1925, Fahr and colleagues noted the resemblance of minimal change disease to focal segmental glomerulosclerosis (FSGS).[1] Ever since its early description, the term “lipoid nephrosis” has been criticized due to the clinical irrelevance of the lipid-laden cells seen on microscopy.
References
- ↑ 1.0 1.1 D'Agati V (2003). "Pathologic classification of focal segmental glomerulosclerosis". Semin Nephrol. 23 (2): 117–34. doi:10.1053/snep.2003.50012. PMID 12704572.