Idiopathic pulmonary fibrosis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Jacquelyne DiTroia
Overview
Pulmonary Fibrosis Causes
Common Causes
The most common causes of pulmonary fibrosis are:
- Autoimmune diseases:
- Rheumatoid arthritis
- Scleroderma (systemic sclerosis)
- Tuberculosis
- Pneumonia
- Systemic lupus erythematosus
- Sarcoidosis
- Polymyositis
- Dermatomyositis
- Anti-synthetase syndrome
- GERD - Gastroesophageal Reflux Disease
Environmental Factors
- Cigarette smoke
- Asbestos exposure
- Silica exposure
- Coal dust exposure
- Beryllium exposure
- Hard metal dusts exposure
- Animal protein exposure
- Bacteria, mold exposure
- Radiation
Drugs
- lomustine
- panitumumab
- penicillamine
- rifapentin
- methotrexate (Trexall)
- cyclophosphamide (Cytoxan)
- amiodarone (Cordarone
- Nexterone, (Pacerone)
- propranolol (Inderol, Innopran)
- nitrofurantoin (Macrobid, Macrodantin)
- sulfasalazine (Azulfidine)
Genetic and Inherited Diseases also make up 10-15% of idiopathic pulmonary fibrosis diagnosis'.
Causes by Organ System
Cardiovascular | No underlying causes |
Chemical / poisoning | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect | methotrexate, Trexall, cyclophosphamide, Cytoxan, amiodarone, Cordarone, Nexterone, Pacerone, propranolol, Inderol, Innopran, nitrofurantoin, Macrobid, Macrodantin, sulfasalazine, Azulfidine |
Ear Nose Throat | No underlying causes |
Endocrine | No underlying causes |
Environmental | Cigarette Smoke, Asbestos, silica, coal dust, beryllium, hard metal dusts, animal proteins, bacteria, molds, Radiation |
Gastroenterologic | Gastroesophageal reflux disease |
Genetic | No underlying causes |
Hematologic | No underlying causes |
Iatrogenic | No underlying causes |
Infectious Disease | Dermatomyositis, Polymyositis |
Musculoskeletal / Ortho | Rheumatoid arthritis |
Neurologic | No underlying causes |
Nutritional / Metabolic | No underlying causes |
Obstetric/Gynecologic | No underlying causes |
Oncologic | No underlying causes |
Opthalmologic | No underlying causes |
Overdose / Toxicity | No underlying causes |
Psychiatric | No underlying causes |
Pulmonary | Tuberculosis, Pneumonia, Anti-synthetase syndrome |
Renal / Electrolyte | No underlying causes |
Rheum / Immune / Allergy | Sarcoidosis, systemic lupus erythematosus, rheumatoid arthritis, lupus pleuritis |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Dental | No underlying causes |
Miscellaneous | No underlying causes |