Anal cancer epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]
Epidemiology
Incidence[1]
- In women and men who do not engage in anal intercourse with other men - 0.9/100,000
- In HIV negative men who engage in anal intercourse with other men - 35/100,000
- In HIV positive men who engage in anal intercourse with other men - (estimated) 60-70/100,000
Anal cancer is uncommon and accounts for only 4% of all cancers of the lower alimentary tract. There are estimated to be 4,650 new cases and 690 deaths from anal cancer in the United States in 2007.[2] Because it is rare and because it occurs in a body part that is rarely discussed, most people are unaware of its existence.
- An examination of squamous cell carcinoma tumor tissues from patients in Denmark and Sweden showed a high proportion of anal cancers to be positive for the types of HPV that are also associated with high risk of cervical cancer (90% of the tumors from women, 100% of the tumors from homosexual men, and 58% of tumors from heterosexual men).[3]