Prolactinoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Overview

The prevalence of prolactinoma in younger age group is 100 per 100,000 individuals.[1]Autopsy studies indicate that 6-25% of the U.S. population have small pituitary tumors. Forty percent of these pituitary tumors produce prolactin, but most are not considered clinically significant. Clinically significant pituitary tumors affect approximately 14 out of 100,000 people in United States.

Epidemiology and Demographics

Although small benign pituitary tumors are fairly common in the general population, symptomatic prolactinomas are uncommon. The prevalence of prolactinoma in younger age group is 100 per 100,000 population.[1]Autopsy studies indicate that 6-25% of the U. S. population have small pituitary tumors. Forty percent of these pituitary tumors produce prolactin, but most are not considered clinically significant. Clinically significant pituitary tumors affect the health of approximately 14 out of 100,000 people in United States. In nonselected surgical series, this tumor accounts for approximately 25-30% of all pituitary adenomas. Some growth hormone (GH)–producing tumors also co-secrete prolactin. Microprolactinomas are much more common than macroprolactinomas.

Gender

Prolactinomas occur more often in women than men.

Age

Prolactinomas rarely occur in children.


References

  1. 1.0 1.1 Ciccarelli A, Daly AF, Beckers A (2005). "The epidemiology of prolactinomas". Pituitary. 8 (1): 3–6. doi:10.1007/s11102-005-5079-0. PMID 16411062.

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