Nasopharyngeal carcinoma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
The incidence of nasopharyngeal carcinoma is approximately 1 per 100,000 individuals in US. It is one of the most common malignancies encountered in Asia, especially China.
Epidemiology
Age
While NPC is seen primarily in middle-aged individuals in Asia, a high proportion of African cases appear in children.
Demographics
NPC is uncommon in the United States and most other nations, representing less than 1 case per 100,000 individuals.[1] but is extremely common in southern regions of China,[2] particularly in Guangdong, accounting for 18% of all cancers in China.[3] NPC is uncommon in the United States and most other nations, but is extremely common in Taiwan and certain regions of China, accounting for 18% of all cancers in the latter nation. The cause of increased risk for NPC in these endemic regions is not entirely clear.[4] Nasopharyngeal carcinomas account for approximately 70% of all primary malignancies of the nasopharynx, and although it is rare in western populations, it is one of the most common malignancies encountered in Asia, especially China.[5]
References
- ↑ "Initiative for Vaccine Research (IVR): Viral cancers". World Health Organization. Retrieved 2 October 2012.
- ↑ Fang W, Li X, Jiang Q, (2008). "Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China". J Transl Med. 6: 32. doi:10.1186/1479-5876-6-32. PMC 2443113. PMID 18570662.
- ↑ Chang E T, Adami H (2006). "The Enigmatic Epidemiology of Nasopharyngeal Carcinoma". Cancer Epidemiol Biomarkers Prev. 15 (10): 1765–1777. doi:10.1158/1055-9965.EPI-06-0353. PMID 17035381.
- ↑ Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor). Modern Surgical Pathology (2 Volume Set). London: W B Saunders. ISBN 0-7216-7253-1.
- ↑ http://radiopaedia.org/articles/nasopharyngeal-carcinoma