Endometrial cancer staging
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
According to the FIGO cancer staging system, there are 4 stages of endometrial cancer.
Staging
Endometrial carcinoma is surgically staged using the FIGO cancer staging system.[1]
- Stage I: tumor confined to the corpus uteri
- Stage IA: no or less than half myometrial invasion
- Stage IB: invasion equal to or more than half of the myometrium
- Stage II : tumor invades cervical stroma but does not extend beyond the uterus
- Stage III: local and/or regional spread of the tumor
- Stage IIIA: tumor invades the serosa of the corpus uteri and/or adnexae
- Stage IIIB: vaginal involvement and/or parametrial involvement
- Stage IIIC: metastases to pelvic and/or para-aortic lymph nodes
- Stage IIIC1: positive pelvic nodes
- Stage IIIC2: positive para-aortic nodes with or without positive pelvic lymph nodes
- Stage IV: tumor invades bladder and/or bowel mucosa, and/or distant metastases
- Stage IVA: tumor invasion of bladder and/or bowel mucosa
- Stage IVB: distant metastasis, including intra-abdominal metastases and/or inguinal nodes
Stage | Findings |
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Stage I | Tumor confined to the corpus uteri |
IA | no or less than half myometrial invasion |
IB | invasion equal to or more than half of the myometrium |
Stage II | tumor invades cervical stroma but does not extend beyond the uterus |
Stage III | local and/or regional spread of the tumor |
IIIA | tumor invades the serosa of the corpus uteri and/or adnexae |
IIIB | vaginal involvement and/or parametrial involvement |
III C | metastases to pelvic and/or para-aortic lymph nodes |
(i) positive pelvic nodes | |
(ii) positive para-aortic nodes with or without positive pelvic lymph nodes | |
Stage IV | tumor invades bladder and/or bowel mucosa, and/or distant metastases |
IVA | Tumor invades any of the following: |
(i) upper urethral and/or vaginal mucosa, bladder mucosa, rectal mucosa, or fixed to pelvic bone, or | |
(ii) fixed or ulcerated inguinofemoral lymph nodes. | |
IVB | Any distant metastasis including pelvic lymph nodes. |