Gliomatosis cerebri MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Brain MRI is helpful in the diagnosis of gliomatosis cerebri. On brain MRI, gliomatosis cerebri is characterized by:^[1]


MRI component	Findings

T1	Iso to hypointense to grey matter
T2	Hyperintense to grey matter
T1C+	No or minimal enhancement
DWI	No restriction
MR spectroscopy	Elevated choline/creatine and choline/NAA ratios Marked elevation of myo-inositol
MR perfusion	Low/normal rCBV Correlates with no vascular hyperplasia

↑ Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Image courtesy of Dr. Henry Knipe and Dr. Frank Gaillard et al. Radiopaedia (original file here').Creative Commons BY-SA-NC