Hypopharyngeal cancer medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Medical Therapy
Treatment Options by Stage: [1]
Stage I Hypopharyngeal Cancer Stage II Hypopharyngeal Cancer Stage III Hypopharyngeal Cancer Stage IV Hypopharyngeal Cancer
Stage I Hypopharyngeal Cancer
Treatment of stage I hypopharyngeal cancer may include the following:
Laryngopharyngectomy and neck dissection with or without high-dose radiation therapy to the lymph nodes of the neck. Partial laryngopharyngectomy with or without high-dose radiation therapy to the lymph nodes on both sides of the neck.
Check the list of NCI-supported cancer clinical trials that are now accepting patients with stage I hypopharyngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI website.
Stage II Hypopharyngeal Cancer
Treatment of stage II hypopharyngeal cancer may include the following:
Laryngopharyngectomy and neck dissection. High-dose radiationtherapy to the lymph nodes of the neck may be given before or after surgery. Partial laryngopharyngectomy. High-dose radiation therapy to the lymph nodes of the neck may be given before or after surgery. Chemotherapy given during or after radiation therapy or after surgery. A clinical trial of chemotherapy followed by radiation therapy or surgery.
Check the list of NCI-supported cancer clinical trials that are now accepting patients withstage II hypopharyngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI website.
Stage III Hypopharyngeal Cancer
Treatment of stage III hypopharyngeal cancer may include the following:
Radiation therapy before or after surgery. Chemotherapy given during or after radiation therapy or after surgery. A clinical trial of chemotherapy followed by surgery and/or radiation therapy. A clinical trial of chemotherapy given at the same time as radiation therapy. A clinical trial of surgery followed by chemotherapy given at the same time as radiation therapy.
Treatment and follow-up of stage III hypopharyngeal cancer is complex and is ideally overseen by a team of specialists with experience and expertise in treating this type ofcancer. If all or part of the hypopharynx is removed, the patient may need plastic surgeryand other special help with breathing, eating, and talking.
Check the list of NCI-supported cancer clinical trials that are now accepting patients withstage III hypopharyngeal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI website.
Stage IV Hypopharyngeal Cancer
Treatment of stage IV hypopharyngeal cancer that can be treated with surgery may include the following:
Radiation therapy before or after surgery. A clinical trial of chemotherapy followed by surgery and/or radiation therapy. A clinical trial of surgery followed by chemotherapy given at the same time as radiation therapy.
Surgical treatment and follow-up of stage IV hypopharyngeal cancer is complex and is ideally overseen by a team of specialists with experience and expertise in treating this type of cancer. If all or part of the hypopharynx is removed, the patient may need plastic surgery and other special help with breathing, eating, and talking.
Treatment of stage IV hypopharyngeal cancer that cannot be treated with surgery may include the following:
Radiation therapy. Chemotherapy given at the same time as radiation therapy. A clinical trial of radiation therapy with chemotherapy.
- The goal of treatment is to completely remove the cancer and prevent it from spreading to other parts of the body.
- When the tumor is larger or has spread to lymph nodes in the neck, a combination of radiation and chemotherapy is often used to preserve the voice box.
Supportive Treatment
Many patients also need swallowing therapy after treatment to help them adjust to the changes in the structure of the throat.