Insulinoma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Insulinoma must be differentiated from autoimmune hypoglycemia, hypoglycemia due to sulfonylurea or insulin abuse, factitious hypoglycemia, noninsulinoma pancreatogenic hypoglycemia syndrome (NIPHS), familial persistent hyperinsulinemia, and nesidioblastosis.

Differential Diagnosis

Insulinoma must be differentiated from:

• Hypoglycemia due to sulfonylurea or insulin abuse

• Autoimmune hypoglycemia

• Factitious hypoglycemia

• Noninsulinoma pancreatogenic hypoglycemia syndrome (NIPHS)
• Familial persistent hyperinsulinemia

• Nesidioblastosis