Neuroblastoma laboratory tests

Neuroblastoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Neuroblastoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Staging
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Neuroblastoma laboratory tests On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Neuroblastoma laboratory tests All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Neuroblastoma laboratory tests
CDC on Neuroblastoma laboratory tests
Neuroblastoma laboratory tests in the news
Blogs on Neuroblastoma laboratory tests
Directions to Hospitals Treating Neuroblastoma
Risk calculators and risk factors for Neuroblastoma laboratory tests

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

An elevated concentration of blood and urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) is suggestive of neuroblastoma.

Laboratory Findings

Complete blood count

• Anemia

Basic metabolic panel

• Elevated catecholamine levels
• Elevated dopamine level
• Elevated vanillylmandelic acid (VMA) level
• Elevated Homovanillic acid (HVA) level
• Elevated lactate dehydrogenase level (>1500 U/ml)
• Elevated neuron-specific enolase level(>100 ng/ml)

Urinalysis

• A 24-hour collection of urine indicates elevated concentration of catecholamine or its metabolites such as :

• Vanillylmandelic acid (VMA)
• Homovanillic acid (HVA)