Papillary thyroid cancer natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Natural History

Complications

Prognosis

Depending on source, the overall 5-year survival rate for papillary thyroid cancer is 96 percent^[1] or 97 percent,^[2] with a 10-year survival rate of 93 percent.^[1]

For a more specific prognosis for individual cases, there are at minimum 13 known scoring systems for prognosis; among the more often used are:

AGES - Age, Grade, Extent of disease, Size
AMES - Age, Metastasis, Extent of disease, Size
MACIS - Metastasis, Age at presentation, Completeness of surgical resection, Invasion (extrathyroidal), Size^[3] (this is a modification of the AGES system). It is probably the most reliable staging method available. Also known as the MAICS system.
TNM staging - Tumor, node, metastasis. Remarkable about the TNM staging for (differentiated) thyroid carcinoma is that the scoring is different according to age.

References

↑ ^1.0 ^1.1 Numbers from National Cancer Database in the US, from Page 10 in: Biersack, H-J; Grünwald, F (Eds) (2005). Thyroid Cancer. Berlin: Springer. ISBN 3-540-22309-6. (Note: Book also states that the 14 percent 10-year survival for anaplastic thyroid cancer was overestimated)
↑ Rounded up to nearest natural number from 96.7 percent as given by eMedicine > Thyroid, Papillary Carcinoma Author: Luigi Santacroce. Coauthors: Silvia Gagliardi and Andrew Scott Kennedy. Updated: Sep 28, 2010
↑ "New York Thyroid Center: Prognosis Staging for Thyroid Cancer". Retrieved 2007-12-22.

Template:WikiDoc Sources

[american-1] 1.0 ^1.1 Numbers from National Cancer Database in the US, from Page 10 in: Biersack, H-J; Grünwald, F (Eds) (2005). Thyroid Cancer. Berlin: Springer. ISBN 3-540-22309-6. (Note: Book also states that the 14 percent 10-year survival for anaplastic thyroid cancer was overestimated)

[2] Rounded up to nearest natural number from 96.7 percent as given by eMedicine > Thyroid, Papillary Carcinoma Author: Luigi Santacroce. Coauthors: Silvia Gagliardi and Andrew Scott Kennedy. Updated: Sep 28, 2010

[titleNew_York_Thyroid_Center:_Prognosis_Staging_for_Thyroid_Cancer-3] "New York Thyroid Center: Prognosis Staging for Thyroid Cancer". Retrieved 2007-12-22.

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