Hepatoblastoma surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Surgical resection, adjuvant chemotherapy prior to resection have been used to treat hepatoblastoma.
Surgery
- The complete surgical resection is the cornerstone of treatment for patients with hepatoblastoma and is the only chance of an optimal clinical result; however, the tumor is often unresectable at the time of diagnosis.
- Chemotherapy has been proven effective in both an adjuvant and neoadjuvant treatment and can shrink tumors.
- It makes them less prone to bleed and delineates the tumor from the surrounding normal parenchyma and vascular structures so as to facilitate the resections.
- Hepatoblastoma is sensitive to such chemotherapy drugs as doxorubicin, cisplatin, vincristine, 5-Fluorouracil and cyclophosphamide.