Papillary thyroid cancer laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Laboratory findings consistent with the diagnosis of papillary thyroid cancer include elevated T3, elevated T4, decreased thyroid stimulating hormone, and presence of tumor markers such as thyroglobulin.
Laboratory Findings
- Laboratory findings consistent with the diagnosis of papillary thyroid cancer include elevated T3, elevated T4, decreased thyroid stimulating hormone, and presence of tumor markers such as thyroglobulin. Thyroglobulin can be used as a tumor marker for well-differentiated papillary thyroid cancer.[1][2]
- Reduced expression of ATP5E is significantly associated with the diagnosis of papillary thyroid cancer and may serve as an early tumor marker of the disease.[3]
References
- ↑ Lin JD (2007). "Thyroglobulin and human thyroid cancer". Clin Chim Acta. 388 (1–2): 15–21. doi:10.1016/j.cca.2007.11.002. PMID 18060877.
- ↑ Tuttle RM, Leboeuf R, Martorella AJ (2007). "Papillary thyroid cancer: monitoring and therapy". Endocrinol. Metab. Clin. North Am. 36 (3): 753–78, vii. doi:10.1016/j.ecl.2007.04.004. PMID 17673127.
- ↑ Hurtado-López, LM; Fernández-Ramírez, F; Martínez-Peñafiel, E; Carrillo Ruiz, JD; Herrera González, NE (16 June 2015). "Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?". Medical science monitor : international medical journal of experimental and clinical research. 21: 1745–51. PMID 26079849.