Hereditary nonpolyposis colorectal cancer surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Surgery is the mainstay of treatment for hereditary nonpolyposis colorectal cancer.[1]
Surgery
Surgical resection is recommended among patients with HPNCC because of the high rate of metachronous colorectal cancer. Subtotal colectomy with ileorectal anastomosis and postsurgical endoscopic rectal surveillance are advised when colorectal cancer develops in the setting of HNPCC. The feasibility of prophylactic surgery of the colon, uterus and ovaries depends on a individual basis for HNPCC patients.[2][3] However, in some cases screen-detected members and symptomatic individuals (mostly in their 30s) are eligible for prophylactic colorectal surgery.
References
- ↑ Treatment of hereditary nonpolyposis colorectal cancer.Wikipedia.https://en.wikipedia.org/wiki/Hereditary_nonpolyposis_colorectal_cancer#Treatment Accessed on December 2, 2015
- ↑ Gryfe R (2009). "Inherited colorectal cancer syndromes". Clin Colon Rectal Surg. 22 (4): 198–208. doi:10.1055/s-0029-1242459. PMC 2796102. PMID 21037810.
- ↑ Schmeler KM, Lynch HT, Chen LM, Munsell MF, Soliman PT, Clark MB, Daniels MS, White KG, Boyd-Rogers SG, Conrad PG, Yang KY, Rubin MM, Sun CC, Slomovitz BM, Gershenson DM, Lu KH (2006). "Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome". N. Engl. J. Med. 354 (3): 261–9. doi:10.1056/NEJMoa052627. PMID 16421367.