Hepatoblastoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

Overview

Hepatoblastoma is a common tumor that tends to affect children aged less than five years.[1] Males are more commonly affected with hepatoblastoma than females.[2] The annual incidence of hepatoblastoma in the United States appears to have doubled from 8 (1975-1983) to 16 (2002-2009) per 100,000 children aged 19 years and younger.[3]

Epidemiology and demographics

Prevalence

Hepatic tumors represent approximately 0.5-2% of all the tumors in children and are responsible for 1-4% of all the solid tumors.[4]

Incidence

The annual incidence of hepatoblastoma in the United States appears to have doubled from 8 (1975-1983) to 16 (2002-2009) per 100,000 children aged 19 years and younger.[3]

Age

Hepatoblastoma commonly affects children aged less than five years.[1] Approximately 90% of the cases occur in patients under 5 years of age and two-thirds of the cases occur in the first 2 years of life. Hepatoblastoma in adolescents and young adults is extremely rare.[4]

Gender

Males are more commonly affected with hepatoblastoma than females.[2]

References

  1. 1.0 1.1 Allan, Bassan J.; Parikh, Punam P.; Diaz, Sofia; Perez, Eduardo A.; Neville, Holly L.; Sola, Juan E. (2013). "Predictors of survival and incidence of hepatoblastoma in the paediatric population". HPB. 15 (10): 741–746. doi:10.1111/hpb.12112. ISSN 1365-182X.
  2. 2.0 2.1 Epidemiology of hepatoblastoma. Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/hepatoblastoma. Accessed on November 6, 2015
  3. 3.0 3.1 Incidence. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015
  4. 4.0 4.1 Madabhavi, Irappa; Patel, Apurva; Choudhary, Mukesh; Aagre, Suhas; Revannasiddaiah, Swaroop; Modi, Gaurang; Anand, Asha; Panchal, Harsha; Parikh, Sonia; Raut, Shreeniwas (2014). "Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity". Case Reports in Pediatrics. 2014: 1–5. doi:10.1155/2014/104543. ISSN 2090-6803.


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