Linitis plastica upper GI endoscopy

	Linitis plastica Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Linitis plastica from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Staging
Diagnostic study of choice
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Linitis plastica upper GI endoscopy On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Linitis plastica upper GI endoscopy All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Linitis plastica upper GI endoscopy
CDC on Linitis plastica upper GI endoscopy
Linitis plastica upper GI endoscopy in the news
Blogs on Linitis plastica upper GI endoscopy
Directions to Hospitals Treating Linitis plastica
Risk calculators and risk factors for Linitis plastica upper GI endoscopy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

On upper GI endoscopy, linitis plastica may show superficial ulcers and/or inflammation. On endoscopic ultrasound, abnormal thickening of the stomach wall is a characteristic finding.^[1]

Esophagogastroduodenoscopy (EGD) or upper GI endoscopy with multiple deep tissue biopsies (like bloc biopsies), is performed and is needed for diagnosis.^[2]
- Mucosa may look innocent or show superficial ulcers as in gastritis and thus, may mask the malignant nature of linitis plastica. Therefore, multiple, deep biopsies are needed to make the diagnosis.
Ultrasound may be performed endoscopically during an Upper GI endoscopy and it helps to understand the depth of tumor invasion as well as spread of the disease to the adjacent structures.
- A 10-20mm thickening of the submucosal layer is usually present.^[1]