Hereditary nonpolyposis colorectal cancer medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
There is no medical treatment for hereditary nonpolyposis colorectal cancer.[1][2] However, HNPCC patients should consider diet optimization and pharmacological prevention.
Medical Therapy
HNPCC patients should consider the following options of medical management:[3]
Diet optimization
Persons with high risk of colorectal cancer should consider a low fat diet with limitations concerning red meat, but with bran and rich in cellulose.
Pharmacological prevention
There are reports that the group of drugs lowering the risk of colorectal cancer includes: aspirin, sulindac, prioxicam, calcium, and vitamin C. The real value of such drugs in cancer prevention in HNPCC cannot be excluded, but is not proven.[1]
References
- ↑ 1.0 1.1 Si JW, Wang L, Ba XJ, Zhang X, Dong Y, Zhang JX, Li WT, Li T (2015). "[Clinicopathological screening of Lynch syndrome: a report of 2 cases and literature review]". Beijing Da Xue Xue Bao (in Chinese). 47 (5): 858–64. PMID 26474631.
- ↑ Hendriks YM, de Jong AE, Morreau H, Tops CM, Vasen HF, Wijnen JT, Breuning MH, Bröcker-Vriends AH (2006). "Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians". CA Cancer J Clin. 56 (4): 213–25. PMID 16870997.
- ↑ Kladny J, Lubinski J. Lynch syndrome (HNPCC). Hered Cancer Clin Pract. 2008;6(2):99-102.