Colorado tick fever pathophysiology
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Overview
Colorado tick fever is an Orbivirus or Colivirus that chronically infects Rocky Mountain wood ticks. The virus typically infects cells in bone marrow causing issues with the development of certain blood cells. Infection is transmitted by the bite of an infected Rocky Mountain wood tick.
Viral classification
- Genera of Colorado tick fever is wither an Orbivirus or Coltivirus.
- Four serotypes are responsible for human infections.[1]
Pathogenisis
- Viral pathway involves targeting the cells in bone marrow or young child's central nervous system.
- Inhibits the proper development of blood cells.
- A host defense mechanism, humoral immunity, is elicited by infection.
References
- ↑ Rotaviruses, Reoviruses, Coltiviruses, and Orbiviruses. http://www.ncbi.nlm.nih.gov/books/NBK8558/ 1996; Accessed January 21, 2016.