Bone or cartilage mass biopsy
|
Bone or Cartilage Mass Microchapters |
|
Diagnosis |
|---|
|
Case Studies |
|
Bone or cartilage mass biopsy On the Web |
|
American Roentgen Ray Society Images of Bone or cartilage mass biopsy |
|
Risk calculators and risk factors for Bone or cartilage mass biopsy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Bone biopsy findings associated with bone and cartilage tumors will depend on tumor histology, common findings include: anastomosing bony trabeculae, calcifications surrounded by cells nests, and increased/decreased osteoblasts and osteoclasts.[1]
Biopsy
Common types of bone biopsy, include:[1]
- Open
- Gold standard for diagnosis of a bone tumor
- Performed during surgery
- On malignant lesions, biopsy incisions are: longitudinal, small, or anatomically placed to minimize contamination of normal tissue
- Increased risk of complications
- Tissue biopsy analyzed for bacterial and fungal culture, because bone infections may mimic a bone tumor
- Closed
- Less invasive and lower risk of tissue contamination with tumor cells
- Usually involves CT guidance
- Less risk of complications
- Less painful, and less costly
- Disadvantages, include: insufficient tissue from lesions and erroneous diagnosis of tumor grade
References
- ↑ 1.0 1.1 Mankin HJ, Lange TA, Spanier SS (2006). "THE CLASSIC: The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. The Journal of Bone and Joint Surgery, 1982;64:1121-1127". Clin. Orthop. Relat. Res. 450: 4–10. doi:10.1097/01.blo.0000229299.36969.b5. PMID 16951637.