Bone or cartilage mass epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Bone and cartilage tumors are uncommon, they represent 0.2% of all neoplasms in general population. The prevalence of bone and cartilage tumors is approximately 0.9 per 100,000 individuals. Bone and cartilage tumors have a bimodal age distribution. These tumors are more frequent in children and adolescents, and older adults. The average age at diagnosis is between 10-25 years old and 60-75 years old. Males are more commonly affected than females, with a 1.5:1 ratio.[1] Bone and cartilage tumors are slightly more common among individuals of Caucasian race.[2]
Epidemiology and Demographics
Prevalence
- The estimated prevalence of bone and cartilage tumors is 0.2% in general population.[1]
- The table below summarizes the frequency order of common primary malignant bone and cartilage tumors.
| Primary bone malignancy | Frequency (%) |
|---|---|
| Osteosarcoma | 35.1 |
| Chondrosarcoma | 25.8 |
| Ewing sarcoma | 16 |
| Chordoma | 8.4 |
| Malignant fibrous histiocytoma | 5.7 |
| Unespecifed | 1.2 |
| Others | 6.4 |
Incidence
- The incidence rate for all bone and cartilage malignant tumors is 0.9 per 100,000 persons per year.[1]
Age
- The age-adjusted incidence rate of malignant bone and cartilage tumors has a bimodal distribution.[1]
- The first peak of incidence has an average age at diagnosis between 10-25 years.
- The second peak of incidence has an average age at diagnosis between 60-75 years.
Gender
- Males are slightly more affected than females. The male-to-female ratio is approximately 1.5 to 1.
Race
- Bone and cartilage tumors are slightly more common among individuals of Caucasian race.[1]