Fibroma differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Differential Diagnosis

Type of Fibroma	Differential Diagnosis
Ovarian fibroma	Large pedunculated subserosal uterine leiomyoma
Non-ossifying fibroma	Fibrous cortical defect Aneurysmal bone cyst Chondromyxoid fibroma Fibrous dysplasia Desmoplastic fibroma
Ossifying Fibroma	Fibrous dysplasia Adamantinoma Osteoid osteoma
Chondromyxoid Fibroma	Aneurysmal bone cyst (ABC) Giant cell tumour of bone (GCT) Non ossifying fibroma Chondroblastoma
Desmoplastic Fibroma	Giant cell tumour of bone (GCT) Non ossifying fibroma (NOF)
Pleural Fibroma	Considerations for extremely well defined lesions include: Pleural lipoma Pleural fibrosarcoma Intercostal nerve neurilemoma (schwannoma) If not extremely well defined, broader considerations include: Organised inflammation Peripheral bronchogenic carcinoma Solitary pleural metastasis Also consider the differential for a single pleural mass which includes the following: Pleural tumours Solitary fibrous tumour of the pleura (pleural fibroma) Mesothelioma Localised mediastinal malignant mesothelioma Metastatic pleural disease, particularly from adenocarcinomas Pleural lymphoma Invasive thymoma Lipoma Pleural effusion Empyema Haemothorax Ewing sarcoma of chest wall, Askin tumour Intercostal nerve neurilemmoma Splenosis Tuberculosis	Desmoplastic Fibroma	Giant cell tumour of bone (GCT) Non ossifying fibroma (NOF)