Aortic stenosis prevention
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Resident Survival Guide |
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Aortic Stenosis Microchapters |
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Diagnosis |
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Treatment |
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Percutaneous Aortic Balloon Valvotomy (PABV) or Aortic Valvuloplasty |
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Transcatheter Aortic Valve Replacement (TAVR) |
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Case Studies |
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Aortic stenosis prevention On the Web |
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American Roentgen Ray Society Images of Aortic stenosis prevention |
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Risk calculators and risk factors for Aortic stenosis prevention |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Mohammed A. Sbeih, M.D. [2]
Overview
The risk of developing aortic stenosis following rheumatic heart disease can be minimized with early antibiotic therapy among patients with documented streptococcal pharyngitis (strep throat).[1] Bicuspid aortic valve disease is a congenital variant and cannot be prevented. As for calcific aortic stenosis, a number of small, observational studies have demonstrated an association between lowering cholesterol levels and decreasing the progression of the aortic stenosis;[2] however, randomized clinical trials have failed to corroborate these findings.[3][4][5]
References
- ↑ Dajani A, Taubert K, Ferrieri P, Peter G, Shulman S (1995). "Treatment of acute streptococcal pharyngitis and prevention of rheumatic fever: a statement for health professionals. Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, the American Heart Association". Pediatrics. 96 (4 Pt 1): 758–64. PMID 7567345.
- ↑ Moura LM, Ramos SF, Zamorano JL; et al. (2007). "Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis". J. Am. Coll. Cardiol. 49 (5): 554–61. doi:10.1016/j.jacc.2006.07.072. PMID 17276178.
- ↑ Rossebø AB, Pedersen TR, Boman K, Brudi P, Chambers JB, Egstrup K; et al. (2008). "Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis". N Engl J Med. 359 (13): 1343–56. doi:10.1056/NEJMoa0804602. PMID 18765433.
- ↑ Cowell SJ, Newby DE, Prescott RJ, Bloomfield P, Reid J, Northridge DB; et al. (2005). "A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis". N Engl J Med. 352 (23): 2389–97. doi:10.1056/NEJMoa043876. PMID 15944423.
- ↑ Chan KL, Teo K, Dumesnil JG, Ni A, Tam J, ASTRONOMER Investigators (2010). "Effect of Lipid lowering with rosuvastatin on progression of aortic stenosis: results of the aortic stenosis progression observation: measuring effects of rosuvastatin (ASTRONOMER) trial". Circulation. 121 (2): 306–14. doi:10.1161/CIRCULATIONAHA.109.900027. PMID 20048204.