Aortic stenosis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Mohammed A. Sbeih, M.D. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]
Overview
The most common risk factor for the development of aortic stenosis is the presence of a congenital bicuspid aortic valve. Risk factors that may speed up the progression of aortic stenosis include the same risk factors as atherosclerosis.
Risk Factors
- Common risk factors for the development of aortic stenosis include:
- Congenital bicuspid aortic valve that may subsequently become calcified later in life
- Acute rheumatic fever
- Age-related progressive calcification of the normal tricuspid aortic valve
- Other risk factors that may speed up the progression of aortic stenosis include the same risk factors as atherosclerosis:
Other risk factors of aortic stenosis include:
- Radiation therapy for cancer, such as breast cancer or lymphoma[3]
- High lipoprotein a[4]
- Disorders of calcium metabolism[5]
References
- ↑ 1.0 1.1 1.2 1.3 Aronow WS, Schwartz KS, Koenigsberg M (1987). "Correlation of serum lipids, calcium, and phosphorus, diabetes mellitus and history of systemic hypertension with presence or absence of calcified or thickened aortic cusps or root in elderly patients". Am J Cardiol. 59 (9): 998–9. PMID 3565291.
- ↑ Lindroos M, Kupari M, Valvanne J, Strandberg T, Heikkilä J, Tilvis R (1994). "Factors associated with calcific aortic valve degeneration in the elderly". Eur Heart J. 15 (7): 865–70. PMID 7925504.
- ↑ Hull MC, Morris CG, Pepine CJ, Mendenhall NP (2003). "Valvular dysfunction and carotid, subclavian, and coronary artery disease in survivors of hodgkin lymphoma treated with radiation therapy". JAMA. 290 (21): 2831–7. doi:10.1001/jama.290.21.2831. PMID 14657067.
- ↑ Gotoh T, Kuroda T, Yamasawa M, Nishinaga M, Mitsuhashi T, Seino Y; et al. (1995). "Correlation between lipoprotein(a) and aortic valve sclerosis assessed by echocardiography (the JMS Cardiac Echo and Cohort Study)". Am J Cardiol. 76 (12): 928–32. PMID 7484833.
- ↑ Linefsky JP, O'Brien KD, Katz R, de Boer IH, Barasch E, Jenny NS; et al. (2011). "Association of serum phosphate levels with aortic valve sclerosis and annular calcification: the cardiovascular health study". J Am Coll Cardiol. 58 (3): 291–7. doi:10.1016/j.jacc.2010.11.073. PMC 3147295. PMID 21737022.