Hepatorenal syndrome historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
Historically, the hepatorenal syndrome was first defined as acute renal failure that occurred in the setting of biliary surgery.[1] The syndrome was soon associated with advanced liver disease.It was determined that kidneys transplanted from patients with hepatorenal syndrome were functional,[2] leading to the hypothesis that hepatorenal syndrome was a systemic process as opposed to renal disease, which affects the renal function.
Historical Perspective
References
- ↑ Helwig FC, Schutz CB. A liver kidney syndrome. Clinical pathological and experimental studies. Surg Gynecol Obstet 1932;55:570-580.
- ↑ Koppel MH, Coburn JW, Mims MM, Goldstein H, Boyle JD, Rubini ME. Transplantation of cadaveric kidneys from patients with hepatorenal syndrome. Evidence for the functional nature of renal failure in advanced liver disease. N Engl J Med. 1969 Jun 19;280(25):1367-71. PMID 4890476