Hepatorenal syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Laboratory Findings

• Complete blood count and differential count - elevated leukocytes due to infection
• Serum electrolytes and renal function - low blood sodium
• Liver function tests - elevated liver parameters (e.g bilirubin, alkaline phosphatase)
• Urinalysis
  • Significant proteinuria or hematuria may be present
  • Increased urine specific gravity and osmolality
  • Urine electrolytes - urine creatinine and sodium. Patients with low urine sodium excretions (< 5 mEq/L) are at a greater risk of developing HRS
• Prothrombin time (PT) - prolonged
• Blood ammonia levels - elevated
• Serum creatinine - elevated
• Blood cultures
• Alpha-fetoprotein
• Blood albumin - decreased