Sickle-cell disease surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
There is generally no role for surgery in the primary management of sickle cell disease. However, certain surgeries can be done for specific complications.
Surgery
Surgery is generally not used for treatment of sickle cell disease. However, elective splenectomy can be performed after the first episode of a splenic sequestration crisis.[1] Cholecystectomy can be done for patients who develop cholecystitis or symptoms of gallbladder disease. The cause of cholecystitis in sickle cell disease is due to the development of bilirubin stones (pigmented stones), which can cause inflammation of the gallbladder.[1] This occurs when hemoglobin breaks down to biliverdin then bilirubin. For patients who develop choledocholithiasis, endoscopic retrograde cholangiopancreatography (ERCP) can be done.
References
- ↑ 1.0 1.1 Ballas SK, Kesen MR, Goldberg MF, Lutty GA, Dampier C, Osunkwo I; et al. (2012). "Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management". ScientificWorldJournal. 2012: 949535. doi:10.1100/2012/949535. PMC 3415156. PMID 22924029.