Cervicitis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]
Overview
Laboratory Findings
- Cervicitis might be a sign of upper genital tract infection and so women who seek medical treatment for a new episode of cervicitis should be assessed for signs of PID and managed for C. trachomatis and for N. gonorrhoeae.
- Women with cervicitis also should be evaluated for the presence of Bacteria vaginosis and trichomoniasis, and offered treatment appropriately.
- Microscopy has low sensitivity in detecting N. gonorrhea and T. vaginalis, because of this symptomatic women with cervicitis and negative microscopy should receive further testing (i.e., culture or other FDA-cleared method).
- Although HSV-2 infection has been associated with cervicitis, the utility of specific testing (i.e., culture or serologic testing) for HSV-2 in this setting is unknown. Standardized diagnostic tests for M. genitalium are not commercially available.
- A finding of >10 WBC in vaginal fluid, in the absence of trichomoniasis, may indicate endocervical inflammation caused specifically by C. trachomatis or N. gonorrhoeae, however, culture is more accurate for gonococcal cervicitis.