Congenital rubella syndrome history and symptoms
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
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Overview
History and Symptoms
Symptoms in the Mother
Rubella infections in adults can be asymptomatic. However, usually a prodrome of cough, coryza, low-grade fever and malaise precedes the eruption of a rash. The typical rash of rubella starts on the face and spreads caudally. In pregnant women and young females, a sequelae of polyarthralgia or polyartheritis follows the rubella infection.
Symptoms in the Infant
Symptoms in the infant may include:[1][2][3][4][5][6][7][8][9]
- Cloudy cornea or white appearance to pupil
- Inattention to sounds, which may be suggestive of deafness
- Developmental delay
- Seizures
- Small head size
- Bulging of the head
- Skin rash at birth
- Yellow discoloration of skin and eyes
- Diarrhea
References
- ↑ Cooper LZ (1985). "The history and medical consequences of rubella". Rev. Infect. Dis. 7 Suppl 1: S2–10. PMID 3890105.
- ↑ Banatvala JE, Brown DW (2004). "Rubella". Lancet. 363 (9415): 1127–37. doi:10.1016/S0140-6736(04)15897-2. PMID 15064032.
- ↑ Cooper LZ, Krugman S (1967). "Clinical manifestations of postnatal and congenital rubella". Arch. Ophthalmol. 77 (4): 434–9. PMID 4164540.
- ↑ Cooper LZ, Ziring PR, Ockerse AB, Fedun BA, Kiely B, Krugman S (1969). "Rubella. Clinical manifestations and management". Am. J. Dis. Child. 118 (1): 18–29. PMID 5815335.
- ↑ De Santis M, Cavaliere AF, Straface G, Caruso A (2006). "Rubella infection in pregnancy". Reprod. Toxicol. 21 (4): 390–8. doi:10.1016/j.reprotox.2005.01.014. PMID 16580940.
- ↑ Lambert N, Strebel P, Orenstein W, Icenogle J, Poland GA (2015). "Rubella". Lancet. 385 (9984): 2297–307. doi:10.1016/S0140-6736(14)60539-0. PMC 4514442. PMID 25576992.
- ↑ Ajij M, Nangia S, Dubey BS (2014). "Congenital rubella syndrome with blueberry muffin lesions and extensive metaphysitis". J Clin Diagn Res. 8 (12): PD03–4. doi:10.7860/JCDR/2014/10271.5293. PMC 4316306. PMID 25654000.
- ↑ Bullens D, Smets K, Vanhaesebrouck P (2000). "Congenital rubella syndrome after maternal reinfection". Clin Pediatr (Phila). 39 (2): 113–6. PMID 10696549.
- ↑ Yazigi A, De Pecoulas AE, Vauloup-Fellous C, Grangeot-Keros L, Ayoubi JM, Picone O (2017). "Fetal and neonatal abnormalities due to congenital rubella syndrome: a review of literature". J. Matern. Fetal. Neonatal. Med. 30 (3): 274–278. doi:10.3109/14767058.2016.1169526. PMID 27002428.