Amoebic liver abscess other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Other Diagnostic Tests

Needle aspiration

• Needle aspiration is used to differentiate between amoebic and pyogenic liver abscess
• The ultrasound and CT are used to guide percutaneous aspiration and drainage.
• The aspirated fluid is odorless unless secondarily infected
• The pathognomonic of the aspirate is the reddish-brown anchovy paste appearance, which indicates that the abscess has been present for weeks.
• The trophozoites are present only in the wall of the abscess. Rest of abscess is composed of lysed leukocytes. {| class="wikitable" !Laboratory Test !Findings |- |Microscopy |*Includes wet preparation, concentration, and permanently stained smears. * |- |Culture Methods | |- |Isoenzyme analysis | |- |Antibody Detection Tests | |- |Antigen Detection Tests | |- |Immunochromatographic assays | |} DNA-Based Diagnostic Tests
• {| class="wikitable" !Laboratory Tests !Findings |- |Manual Methods | |- |Automated Methods | |- |Conventional PCR | |- |Real Time PCR | |- |Microarray Development | |- |Typing Methods | |}