Q fever natural history, complications, and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Natural history
Acute Q fever
If left untreated, most patients will recover within several month.
Chronic Q fever
- If left untreated, it is usually deadly. However, with appropriate treatment this lethality is around 10%
Complications
Pulmonary complications
- Atypical pneumonia
- ARDS in rare cases
Cardiac complications
- Endocarditis
- Pericarditis or myocarditis
- Pericarditis and pericardial effusion
Hepatic complications
- Hepatic fibrosis and cirrhosis
Musculoskeletal complications
- Osteomyelitis
- Arthritis
Obstetric complications
- Abortion
- IUGR
- IUFD
Prognosis
Acute Q fever
Acute Q fever is responsive to treatment and even without treatment, mortality is 1-2%
Chronic Q fever
Chronic Q fever is more serious with lethaity of 10% after treatment.