Filariasis differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Mohammed Abdelwahed M.D [2]

Diseases	Symptoms	Signs	Investigations
Lymphatic filariasis		row 1, cell 3
Chronic venous insufficiency	History of untreated varicose veins Painful bilateral lower limb swelling increase with standing and decreased by rest and leg elevation	Typical varicose veins Skin change distribution correlate with varicose veins sites in the medial side of ankle and leg Reduction of swelling with limb elevation.	Duplex ultrasound will demonstrate typical findings of venous valvular insufficiency
Acute deep venous thrombosis	History of prolonged recumbency Classic symptoms of DVT include acute unilateral swelling, pain, and erythema		Compression ultrasonography (CUS) with Doppler is the diagnostic test of choice D-dimer is used for unprobable cases
Lipedema	Patients may complain of pain,swelling and easy bruising.^[1]	Family history especially in women; X-linked dominant or autosomal dominant condition^[2] Abnormal deposition of fat and edema Tenderness with palpation
Myxedema	History of untreated hypothyroidism
Cellulitis
Other causes of generalized edema

References

↑ Herbst KL (2012). "Rare adipose disorders (RADs) masquerading as obesity". Acta Pharmacol Sin. 33 (2): 155–72. doi:10.1038/aps.2011.153. PMC 4010336. PMID 22301856.
↑ Child AH, Gordon KD, Sharpe P, Brice G, Ostergaard P, Jeffery S; et al. (2010). "Lipedema: an inherited condition". Am J Med Genet A. 152A (4): 970–6. doi:10.1002/ajmg.a.33313. PMID 20358611.