Hyperparathyroidism epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Epidemiology and Demographics

There is insufficient data on epidemiology and demographics of secondary and tertiary hyperparathyroidism.

Primary hyperparathyroidism

Epidemiology and demographics of primary hyperparathyroidism is as follows:

Incidence

• The incidence of primary hyperparathyroidism is approximately 0.4 to 21.6 per 100,000 person years.

Prevalence

• The prevalence of primary hyperparathyroidism is approximately .01 to .07 per 100,000 individuals.

Age

• The incidence of primary hyperparathyroidism increases with age.
• In individuals age < 50 years, the incidence of primary hyperparathyroidism ranges from a low of 12 per 100,000 person years to a high of 24 per 100,000 per person years.

Race

• Primary hyperparathyroidism usually affects individuals of African-American race.
• The incidence of primary hyperparathyroidism according to race is as follows:

Incidence of Primary hyperparathyroidism according to race
Race	Gender (incidence per 100,000 person years)
	Women	Men
African-American	92	46
White	81	29
Asian	52	28
Hispanic	49	17
Other race	25	6

Gender

• Women are more commonly affected by primary hyperparathyroidism than men. The women to men ratio is approximately 3 to 1.
• In women, the incidence of primary hyperparathyroidism ranges from a low of 34 per 100,000 person years to a high of 120 per 100,000 person years with an average incidence of 66 per 100,000 person years.
• In men, the incidence of primary hyperparathyroidism ranges from a low of 13 per 100,000 person years to a high of 36 per 100,000 person years with an average incidence of 24 per 100,000 person years.
• Difference in gender specific incidence of primary hyperparathyroidism becomes more pronounced with advancing age.

Incidence of primary hyperparathyroidism in different age group
Age group	Gender (incidence per 100,000 person years)
	Women	Men
Age < 50 years	12-24	12-24
Age 50 - 59 years	80	36
Age 70-79 years	196	95

Region

• The majority of [disease name] cases are reported in [geographical region].

• [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].