Insulinoma MRI
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Insulinoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Insulinoma MRI On the Web |
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American Roentgen Ray Society Images of Insulinoma MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
MRI has better sensitivity than CT scan.
MRI
MRI is superior in detecting insulinoma in that it has greater sensitivity currently ~85%. In a study of 21 insulinomas by Owen et al,the sensitivity was noted to be 94%.(19/21 cases). The 2 cases were of 5 and 7 mm size and in pancreatic tail[1][2]
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Insulinoma T1 fat sat- Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma (Axial T1 C+fat sat)Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma (Axial T2 fat sat)Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma(T1C+ PV)Case courtesy of Dr Andrew Dixon, Radiopaedia.org, rID: 10407 -
Insulinoma- Case courtesy of Dr J. Ray Ballinger, Radiopaedia.org, rID: 23627 -
Insulinoma-Case courtesy of Dr Alejandro Cruz, Radiopaedia.org, rID: 30096
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- T1 and T2 relaxation times for islet cell tumor like insulinoma has lower protein and proton concentration time
- Abdominal MRI may be helpful in the diagnosis of insulinoma. Findings on MRI suggestive of Insulinoma include[3]:
- Low in signal intensity on fat suppressed T1-weighted images
- High on intensity on fat suppressed T2-weighted images independent of lesion size
- Enhancement patterns are due to hypervascularity. Homogenous enhancement is exhibited commonly in insulinoma, ring enhancement if they are larger than 2 cm.
- same pattern can be seen in metastatic lymph node as of the primary; homogenous when small and ring enhancement if tumor is more than 2 cm.
References
- ↑ Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.
- ↑ Thoeni RF, Mueller-Lisse UG, Chan R, Do NK, Shyn PB (2000). "Detection of small, functional islet cell tumors in the pancreas: selection of MR imaging sequences for optimal sensitivity". Radiology. 214 (2): 483–90. doi:10.1148/radiology.214.2.r00fe32483. PMID 10671597.
- ↑ Noone TC, Hosey J, Firat Z, Semelka RC (2005). "Imaging and localization of islet-cell tumors of the pancreas on CT and MRI". Best Pract Res Clin Endocrinol Metab. 19 (2): 195–211. doi:10.1016/j.beem.2004.11.013. PMID 15763695.