Hypoaldosteronism natural history, complications and prognosis

Hypoaldosteronism Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

OR

Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].

OR

Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

• If left untreated, hypoaldosteronism from Addison's disease can be life-threatening. Any stressful event or illness can cause a sudden worsening of symptoms (in patients of hypoaldosteronism from Addison's) which can lead to severe dehydration and fatally low blood pressure and eventually death.

Complications

• Common complications of [disease name] include:
  • Hyperkalemia
  • Hyponatremia (from urinary sodium wasting)
  • Hypotension
  • Hypovolemia
  • Metabolic acidosis

Prognosis

• Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
• Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
• The presence of hyperkalemia is associated with cardiac arrhythmias which can be fatal.
• [Subtype of disease/malignancy] is associated with the most favorable prognosis.