Hypoaldosteronism history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Hypoaldosteronism often has a gradual onset. Patients of hypoaldosteronism should be enquired about the use of drugs that can alter aldosterone production or function. These drugs include ACEi, ARB and NSAID. The most common symptoms of hypoaldosteronism include fatigue, muscle weakness, and low blood pressure. Other less common symptoms of hypoaldosteronism include hyperpigmentation, gastrointestinal disturbances, and abdominal pain.
A positive history of hypotension, muscle weakness and fatigue should raise suspicion for hypoaldosteronism.
History and Symptoms
History
Obtaining a history gives important information in making a diagnosis of hypoaldosteronism. It provides an insight into the cause, precipitating factors, and associated comorbid conditions. A complete history will help determine the correct therapy and helps in determining the prognosis. Hypoaldosteronism patients are usually asymptomatic. Patients with hypoaldosteronism may have a positive history of:
- Renal disease
- Diabetes mellitus
- History of fatigue
- Episodes of lightheadedness and palpitations
- Drug use such as ACEi, ARB and NSAID
- Craving for salty food
Common Symptoms
Common symptoms of hypoaldosteronism include:
- Chronic fatigue
- Low blood pressure
- Lightheadedness
- Palpitations
- Muscle weakness
- Anorexia
- Weight loss
- Salt craving
- Dizziness
Less Common Symptoms
Less common symptoms of hypoaldosteronism include:
- Hyperpigmentation
- Gastrointestinal disturbances
- Abdominal pain
- Depression