Incidentaloma secondary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Effective measures for the secondary prevention of [disease name] include [strategy 1], [strategy 2], and [strategy 3].
Secondary Prevention
- Effective measures for the secondary prevention of [disease name] include:
- Excess hormone secretion may develop in up to 20% of patients with previously nonfunctional adrenal tumors during follow- up (37, 38, 123).
- The transformation rate of nonfunctional adrenal masses to functional tumors seems to be higher in adrenal masses greater than 3 cm in size (38).
- Annual biochemical follow-up for up to 5 yr may be reasonable for patients with adrenal incidentalomas, especially if the tumor is more than 3 cmin size (20, 21, 37, 45).
- No routine follow-up of adrenal incidentalomas with a non-contrast attenuation value no greater than 10 HU.
- Malignancy can be detected by an absolute increase in size of 0.8 cm, 0.64 cm growth per year, or a 25% increase in size per year.[1]
- A one-time follow-up scan in 6–12 months may be reassuring to the physician and the patient (2, 12, 40, 124).
- Patients with adrenal masses less than 4 cm in size and a non-contrast attenuation value more than 10 HU should have a repeat CT study in 3–6 months and then yearly for 2 yr.
- Surgical excision may be considered for tumors with indeterminate radiological features that grow at least 0.8 cm over 3- to 12-month follow-up (10).
References
- ↑ Pantalone KM, Gopan T, Remer EM, Faiman C, Ioachimescu AG, Levin HS; et al. (2010). "Change in adrenal mass size as a predictor of a malignant tumor". Endocr Pract. 16 (4): 577–87. doi:10.4158/EP09351.OR. PMID 20150023.