Primary biliary cirrhosis classification
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Primary Biliary Cirrhosis Microchapters |
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Differentiating Primary Biliary Cirrhosis from other Diseases |
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Primary biliary cirrhosis classification On the Web |
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American Roentgen Ray Society Images of Primary biliary cirrhosis classification |
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Risk calculators and risk factors for Primary biliary cirrhosis classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]
Overview
There is no established system for the classification of Primary biliary cirrhosis. However, it can be classified into four stages depending on the histology of the disease.[1]
Classification
There is no established system for the classification of primary biliary cirrhosis. However, it can be classified into four stages according to histological classification of Ludwig. According to Ludwig classification, all four stages may be present on a single liver biopsy.[1][2]
Stage 0
- Normal liver
Stage 1
- Stage 1 is characterized by portal inflammation.
Stage 2
- Extension of inflammation beyond portal tracts into surrounding parenchyma with or without ductal loss.
Stage 3
- There is presence of fibrous septa linking adjacent portal tracts.
Stage 4
- Stage 4 is characterized by cirrhosis.
References
- ↑ 1.0 1.1 Lindor KD, Gershwin ME, Poupon R, Kaplan M, Bergasa NV, Heathcote EJ; et al. (2009). "Primary biliary cirrhosis". Hepatology. 50 (1): 291–308. doi:10.1002/hep.22906. PMID 19554543.
- ↑ Ludwig J, Dickson ER, McDonald GS (1978). "Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)". Virchows Arch A Pathol Anat Histol. 379 (2): 103–12. PMID 150690.