Irritable bowel syndrome historical perspective

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sudarshana Datta, MD [2]

Overview

Historical Perspective

Discovery

Diagnostic criteria Symptoms, signs and labs
1978: Manning A threshold of atleast three positive symptoms needs to be present to diagnose IBS with no duration of symptoms described under this classification.

1)     Loose stools with onset of pain

2)     Increased frequency of stools with onset of pain

3)     Mucus per rectum

4)     Visible distension of abdomen reported by the patient

5)     Pain in the abdomen relieved by defecation

6)     Sensation of incomplete evacuation

1984: Kruis
1990: Rome Ⅰ
1999: Rome Ⅱ
2006: Rome Ⅲ
2016: Rome IV
  • [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
  • The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
  • In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
  • In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].

Outbreaks

  • There have been several outbreaks of [disease name], which are summarized below:

Landmark Events in the Development of Treatment Strategies

  • In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].

Impact on Cultural History

Famous Cases

References

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