Irritable bowel syndrome historical perspective
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Irritable bowel syndrome Microchapters |
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Differentiating Irritable bowel syndrome from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Irritable bowel syndrome historical perspective On the Web |
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American Roentgen Ray Society Images of Irritable bowel syndrome historical perspective |
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Risk calculators and risk factors for Irritable bowel syndrome historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sudarshana Datta, MD [2]
Overview
Historical Perspective
Discovery
| Diagnostic criteria | Symptoms, signs and labs |
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| 1978: Manning | A threshold of at least three positive symptoms needs to be present to diagnose IBS with no duration of symptoms described under this classification.
1) Loose stools with onset of pain 2) Increased frequency of stools with onset of pain 3) Mucus per rectum 4) Visible distension of abdomen reported by the patient 5) Pain in the abdomen relieved by defecation 6) Sensation of incomplete evacuation |
| 1984: Kruis | Symptoms of IBS must be present for more than two years. These symptoms include the following:
1. Pain in the abdomen, flatulence 2. Alternating constipation and diarrhea Signs that exclude IBS are determined by the physician. They are as follows: 1. Abnormal physical findings and/or history suggestive of any other diagnosis 2. ESR more than 20mm/2h 3. Anemia(Hemoglobin < 12 for women or < 14 for men) 4. Leukocytosis > 10000/cc Bleeding per rectum found on physical exam |
| 1990: Rome Ⅰ | Abdominal discomfort or pain relieved with defecation or associated with change in frequency or consistency of stool in addition to two or more of the following (on at least twenty five percent of occasions/days for three months):
1. Altered stool form 2. Altered stool frequency 3. Altered stool passage 4. Passage of mucus in stool 5. Abdominal bloating or distension |
| 1999: Rome Ⅱ | Pain in the abdomen or abdominal discomfort that has two of the following three features for twelve weeks(which may not be consecutive) in the last one year:
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| 2006: Rome Ⅲ | Recurrent pain in the abdomen or discomfort for three days in a month, for the last 3 months, associated with two or more of the following:
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| 2016: Rome IV | To establish the diagnosis, the patient must have recurrent pain in the abdomen (On an average, ≥1 day per week, in the previous 3 months) with an onset of ≥6 months before diagnosis-
Pain in the abdomen must be associated with at least two of the following:
Patient must have none of the following warning signs:
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- [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
- The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
- In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
- In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
Outbreaks
- There have been several outbreaks of [disease name], which are summarized below:
Landmark Events in the Development of Treatment Strategies
- In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
Impact on Cultural History
Famous Cases
- The following are a few famous cases of disease name: