Irritable bowel syndrome natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].[1][2]
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of IBS usually develop in the second decade of life, and start with symptoms such as abdominal pain, diarrhea and constipation.
- The symptoms of (disease name) typically develop after exposure to early life adverse events, sexual abuse, anxiety, depression and stressors. Psychological conditions may also develop as complications of the disease. [3][4][5][6]
- If left untreated, patients with IBS may progress to develop malnutrition(resulting from food intolerance), impacted bowel, and poor quality of life.[7] [8][9]
Complications
Complications of irritable bowel syndrome may include:
- Dehydration in case of diarrhea predominant IBS leading to loss of water and electrolytes.[10]
- Impacted bowel [11]
- Hemorrhoids [12][13]
- Depression and anxiety [3][4][5][6]
- Fatigue [14]
- Decline in quality of life[7] [8][9]
- Malnutrition, resulting from food intolerance
Prognosis
Irritable bowel syndrome may be a life-long condition, but symptoms can often be improved or relieved through treatment.
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ El-Serag HB, Pilgrim P, Schoenfeld P (2004). "Systemic review: Natural history of irritable bowel syndrome". Aliment. Pharmacol. Ther. 19 (8): 861–70. doi:10.1111/j.1365-2036.2004.01929.x. PMID 15080847.
- ↑ Olafsdottir LB, Gudjonsson H, Jonsdottir HH, Björnsson E, Thjodleifsson B (2012). "Natural history of irritable bowel syndrome in women and dysmenorrhea: a 10-year follow-up study". Gastroenterol Res Pract. 2012: 534204. doi:10.1155/2012/534204. PMC 3312222. PMID 22474441.
- ↑ 3.0 3.1 Klem F, Wadhwa A, Prokop LJ, Sundt WJ, Farrugia G, Camilleri M, Singh S, Grover M (2017). "Prevalence, Risk Factors, and Outcomes of Irritable Bowel Syndrome After Infectious Enteritis: A Systematic Review and Meta-analysis". Gastroenterology. 152 (5): 1042–1054.e1. doi:10.1053/j.gastro.2016.12.039. PMID 28069350.
- ↑ 4.0 4.1 Hausteiner-Wiehle C, Henningsen P (2014). "Irritable bowel syndrome: relations with functional, mental, and somatoform disorders". World J. Gastroenterol. 20 (20): 6024–30. doi:10.3748/wjg.v20.i20.6024. PMC 4033442. PMID 24876725.
- ↑ 5.0 5.1 Fond G, Loundou A, Hamdani N, Boukouaci W, Dargel A, Oliveira J, Roger M, Tamouza R, Leboyer M, Boyer L (2014). "Anxiety and depression comorbidities in irritable bowel syndrome (IBS): a systematic review and meta-analysis". Eur Arch Psychiatry Clin Neurosci. 264 (8): 651–60. doi:10.1007/s00406-014-0502-z. PMID 24705634.
- ↑ 6.0 6.1 Csef H, Bornhauser N (2003). "[Psychosomatic aspects of chronic diarrhea]". MMW Fortschr Med (in German). 145 (50): 35–7. PMID 14963969.
- ↑ 7.0 7.1 Chakiath RJ, Siddall PJ, Kellow JE, Hush JM, Jones MP, Marcuzzi A, Wrigley PJ (2015). "Descending pain modulation in irritable bowel syndrome (IBS): a systematic review and meta-analysis". Syst Rev. 4: 175. doi:10.1186/s13643-015-0162-8. PMC 4674951. PMID 26652749.
- ↑ 8.0 8.1 Farndale R, Roberts L (2011). "Long-term impact of irritable bowel syndrome: a qualitative study". Prim Health Care Res Dev. 12 (1): 52–67. doi:10.1017/S1463423610000095. PMID 21426615.
- ↑ 9.0 9.1 Lea R, Whorwell PJ (2004). "Psychological influences on the irritable bowel syndrome". Minerva Med. 95 (5): 443–50. PMID 15467519.
- ↑ Morley JE, Steinberg KE (2009). "Diarrhea in long-term care: a messy problem". J Am Med Dir Assoc. 10 (4): 213–7. doi:10.1016/j.jamda.2009.01.007. PMID 19426933.
- ↑ Mearin F, Ciriza C, Mínguez M, Rey E, Mascort JJ, Peña E, Cañones P, Júdez J (2016). "Clinical Practice Guideline: Irritable bowel syndrome with constipation and functional constipation in the adult". Rev Esp Enferm Dig. 108 (6): 332–63. doi:10.17235/reed.2016.4389/2016. PMID 27230827.
- ↑ Arora G, Mannalithara A, Mithal A, Triadafilopoulos G, Singh G (2012). "Concurrent conditions in patients with chronic constipation: a population-based study". PLoS ONE. 7 (10): e42910. doi:10.1371/journal.pone.0042910. PMC 3470567. PMID 23071488.
- ↑ Tan KY, Seow-Choen F (2007). "Fiber and colorectal diseases: separating fact from fiction". World J. Gastroenterol. 13 (31): 4161–7. PMC 4250613. PMID 17696243.
- ↑ Han CJ, Yang GS (2016). "Fatigue in Irritable Bowel Syndrome: A Systematic Review and Meta-analysis of Pooled Frequency and Severity of Fatigue". Asian Nurs Res (Korean Soc Nurs Sci). 10 (1): 1–10. doi:10.1016/j.anr.2016.01.003. PMID 27021828.