Radiation proctitis pathophysiology

Radiation proctitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Pathophysiology

• Acute radiation proctitis is due to direct damage of the lining (epithelium) of the colon.
• Chronic radiation proctitis occurs in part because of damage to the blood vessels which supply the colon. The colon is therefore deprived of oxygen and necessary nutrients.