Gastric dumping syndrome diagnostic study of choice

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

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Overview

The two most sensitive and specific tests used in confirming the clinical suspicion and in diagnosing Dumping syndrome. They are the oral glucose tolerance test and the Hydrogen breath test.

Diagnostic Study of Choice

Study of choice:

• Oral glucose tolerance test is the study of choice for the diagnosis of early dumping syndrome and late dumping syndrome.
• A mixed-meal tolerance test is the study of choice for the diagnosis of late dumping syndrome.

The comparison table for diagnostic studies of choice for Dumping syndrome

	Table	Sensitivity	Specificity
	✔ Oral glucose provocation	100%	92%
	Hydrogen breath	100%	?

✔= The best test based on the feature

Diagnostic results

The following result of the oral glucose tolerance test is confirmatory of dumping syndrome:

• An increase in the heart rate by 10 beats per minute or more in the first hour after an oral glucose challenge of 50 grams glucose after fasting for 10 hours.

The following result of the Hydrogen breath test is confirmatory of dumping syndrome:

• A positive Hydrogen breath test after glucose ingestion.

Diagnostic Criteria

Oral glucose tolerance test
The patient fasts overnight. An oral glucose load of 50 grams or 75 grams in solution is given. Readings of the heart rate and blood pressure are taken before the ingestion Blood is drawn before the ingestion. Then after ingestion, every 30 minutes until 180 minutes, readings and blood are taken. If the patient has an

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