Colon polyps classification

Colon polyps Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]

Overview

Colon polyps may be classified into two groups of neoplastic and nonneoplastic. Non-neoplastic polyps consist of inflammatory and hamartomatous polyps. Neoplastic polyps consist of serrated and adenomatous polyps. Adenomatous polyps may be classified into several subtypes based on endoscopic, histologic features and degree of dysplasia. Adenomas may be classified according to endoscopic features into four groups including sessile, pedunculated, flat, or depressed. Adenomas may be classified according to histologic features into three groups including tubular, tubulovillous, and villous.

Classification

• Colon polyps may be classified into two groups:
  • Non-neoplastic
    • Inflammatory polyps
      • Inflammatory pseudopolyps
      • Prolapse type inflammatory polyps
      • Myoglandular polyps
    • Hamartomatous polyps
      • Juvenile polyps
      • Peutz-Jeghers polyps
      • Cronkhite-Canada syndrome
      • Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome
  • Neoplastic
    • Serrated polyps
      • Hyperplastic polyps
      • Traditional serrated adenomas
      • Sessile serrated polyps
      • Serrated polyposis syndrome
    • Adenomatous polyps

Adenomatous polyps may be classified into several subtypes based on:

• Endoscopic features
• Histologic features
• degree of dysplasia

Adenomas may be classified according to endoscopic features into four groups:

• Sessile
• Pedunculated
• Flat
• Depressed

Adenomas may be classified according to histologic features into three groups:

• Tubular
• Villous
• Tubulovillous

Adenomas may be classified according to degree of dysplasia into two groups:

• Low-grade dysplasia
• High-grade dysplasia