Autoimmune hepatitis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: :Manpreet Kaur, MD [2]

Risk Factors

Common Risk Factors

• Common risk factors in the development of Autoimmune hepatitis include:
  • Autoimmune hepatitis is more common in females
  • Genetic predisposition:
    • Autoimmune hepatitis type 1 has the association with HLA-DR3 and HLA-DR4
  • Type 2 AIH has been associated with the HLA-DQB1 and HLA-DRB1 alleles.

Less Common Risk Factors

• Less common risk factors in the development of Autoimmune hepatitis include:
  • History of another autoimmune disease
  • History of drug intake like minocycline, interferon