Sinusoidal obstruction syndrome natural history, complications and prognosis
|
Sinusoidal obstruction syndrome Microchapters |
|
Differentiating Sinusoidal obstruction syndrome from Other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Sinusoidal obstruction syndrome natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Sinusoidal obstruction syndrome natural history, complications and prognosis |
|
FDA on Sinusoidal obstruction syndrome natural history, complications and prognosis |
|
CDC on Sinusoidal obstruction syndrome natural history, complications and prognosis |
|
Sinusoidal obstruction syndrome natural history, complications and prognosis in the news |
|
Blogs on Sinusoidal obstruction syndrome natural history, complications and prognosis |
|
Directions to Hospitals Treating Sinusoidal obstruction syndrome |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
Natural History
- Sinusoidal obstruction syndrome is a common complication in patients with hematopoietic stem cell transplant.
- If left untreated, the severe form of sinusoidal obstruction syndrome is characterized by high mortality and progression to multiorgan failure.[1]
Complications
- Complications that can develop as a result of sinusoidal obstruction syndrome are:[2][3][4][5]
Prognosis
- Sinusoidal obstruction syndrome is considered mild, moderate or severe based on the clinical course during the first three months of hematopoietic cell transplantation.[6]
- Patients with a mild or moderate form of sinusoidal obstruction syndrome requires no specific therapy and can be managed with supportive care alone and generally has a good prognosis.[7]
- Patients with the severe sinusoidal obstruction syndrome has a high rate of mortality and can progress to multiorgan failure.[8]
References
- ↑ Coppell JA, Richardson PG, Soiffer R, Martin PL, Kernan NA, Chen A; et al. (2010). "Hepatic veno-occlusive disease following stem cell transplantation: incidence, clinical course, and outcome". Biol Blood Marrow Transplant. 16 (2): 157–68. doi:10.1016/j.bbmt.2009.08.024. PMC 3018714. PMID 19766729.
- ↑ Grus T, Lambert L, Grusová G, Banerjee R, Burgetová A (2017). "Budd-Chiari Syndrome". Prague Med Rep. 118 (2–3): 69–80. doi:10.14712/23362936.2017.6. PMID 28922103.
- ↑ Lin M, Zhang F, Wang Y, Zhang B, Zhang W, Zou X, Zhang M, Zhuge Y (2017). "Liver cirrhosis caused by chronic Budd-Chiari syndrome". Medicine (Baltimore). 96 (34): e7425. doi:10.1097/MD.0000000000007425. PMC 5571988. PMID 28834866.
- ↑ Lane ER, Hsu EK, Murray KF (2015). "Management of ascites in children". Expert Rev Gastroenterol Hepatol. 9 (10): 1281–92. doi:10.1586/17474124.2015.1083419. PMID 26325252.
- ↑ Johnson DB, Savani BN (2012). "How can we reduce hepatic veno-occlusive disease-related deaths after allogeneic stem cell transplantation?". Exp Hematol. 40 (7): 513–7. doi:10.1016/j.exphem.2012.04.004. PMID 22542577.
- ↑ McDonald GB, Hinds MS, Fisher LD, Schoch HG, Wolford JL, Banaji M, Hardin BJ, Shulman HM, Clift RA (1993). "Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients". Ann. Intern. Med. 118 (4): 255–67. PMID 8420443.
- ↑ Fan CQ, Crawford JM (2014). "Sinusoidal obstruction syndrome (hepatic veno-occlusive disease)". J Clin Exp Hepatol. 4 (4): 332–46. doi:10.1016/j.jceh.2014.10.002. PMC 4298625. PMID 25755580.
- ↑ Lopes JA, Jorge S (2011). "Acute kidney injury following HCT: incidence, risk factors and outcome". Bone Marrow Transplant. 46 (11): 1399–408. doi:10.1038/bmt.2011.46. PMID 21383682.