Multiple sclerosis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
Natural History
Complications
Prognosis
there are some factors associated with a particularly poor prognosis among patients with multiple sclerosis although We can’t surly say what is the prognosis of MS patients.
Relapsing versus progressive disease
Progressive form of MS seems to have worse prognosis in comparison to relapsing remitting form of MS. Disabilities start sooner in progressive form (3_15_13) but some studies showed that age of onset is more important in MS disability than the form of the disease (18_47)
Early symptoms
Some first manifestations of MS disease like bowel and bladder dysfunction, seems to have a worse prognosis (48). Another study demonstrated that having so many symptoms at the onset of the disease have a worse prognosis than being monosymptom.(8)
Demographics
Onset of MS in Black Americans is in later age and they are more susceptile of having multifocal signs and symptoms and involvement of optic nerve and spinal cord.(58)
Sex
Women seems to have younger age of onset and so better prognosis than men.(3)
Smoking
Transition of RRMS to SPMS can be accelerated with smoking.(60)