Large cell carcinoma of the lung history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
The hallmark of large cell carcinoma of the lung is non-productive chronic cough, weight loss, and fatigue. A positive history of smoking, exposure to asbestos, or a high risk occupation may be suggestive of large cell carcinoma of the lung. Symptoms related with large cell carcinoma of the lung will vary depending on the size and location of the tumor. Common symptoms of large cell carcinoma of the lung may also include: shortness of breath, fatigue, and chest pain.
History
- Obtaining the history is an important aspect of making a diagnosis of large cell carcinoma of the lung. It provides insight into natural evolution of the disease. Complete history will help determine the likelihood of metastases, and the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:[1][2][3]
- Family history of cancer
- Personal history of cancer
- Positive history of active/passive smoking
- Number of cigarettes/year
- Number of years/months of active smoking
- Number of years/months of smoking cessation
- High occupational risk
- Exposure to asbestos or other chemicals
Common Symptoms
- The majority of large cell carcinoma of the lungs are asymptomatic and are usually found incidentally.[2]
- The hallmark of large cell carcinoma of the lung is chronic cough, weight loss, and hemoptysis.
- Other symptoms that suggest large cell carcinoma of the lung, include:[4][5]
- Dyspnea
- Hemoptysis
- Chronic coughing
- Wheezing
- Chest pain
- Abdominal pain
- Cachexia
- Fatigue
- Loss of appetite
- Dysphonia
Less Common Symptoms
- Other less common symptoms of large cell carcinoma of the lung, include:
References
- ↑ Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
- ↑ 2.0 2.1 Large cell carcinoma of the lung. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016
- ↑ Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM (2007). "Natural history of stage I large cell carcinoma of the lung: implications for early detection". Chest. 132 (1): 193–9. doi:10.1378/chest.06-3096. PMID 17505036.
- ↑ Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter
|coauthors=ignored (help) - ↑ Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015