Idiopathic pulmonary fibrosis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory findings
Laboratory findings consistent with the diagnosis of idiopathic pulmonary fibrosis include:
- Abnormal ABG
- May indicate hypoxia, hypercapnia, and respiratory acidosis
- Abnormal sputum analysis
- May contain bacteria, such as mycobacterium tuberculosis or inorganic particles, such as asbestos bodies or organic particles
- Peak flow assessment
- May be below normal range which is 100 liters/minute for men, and 80 liters/minute for women
- Spirometry
- May indicate a restrictive pulmonary disease
- A FEV1/FVC ratio > 80% indicates restrictive disease
- CBC
- May indicate anemia, neutrophilia, elevated ESR, elevated CRP, and elevated immunoglobulin
- Tuberculin skin test
- To test for tuberculosis, and induration > 5mm is positive
- Stool examination for occult blood
- May indicate colorectal carcinoma